Corticosteroid creams, solutions, gels, foams, and ointmentscan quickly relieve itching and reduce inflammation. They come in various strengths, from mild over-the-counter (OTC) treatments to stronger prescription medicines.
OTC hydrocortisone is often the first thing doctors recommend to treat mild eczema. You may need different strengths of these steroids, depending on where and how bad your rash is. For example, a doctor may prescribe a more potent one for thick, scaly skin.
PDE4 inhibitors
Prescription nonsteroidal anti-inflammatory ointments called crisaborole (Eucrisa) and difamiliast (Adquey) treat mild to moderate forms of eczema. They work by blocking an enzyme that causes inflammation. Another option, roflumilast (Zoryve) cream, can also treat mild to moderate atopic dermatitis. A concentration of 0.15% is approved for adults and kids 6 and up, and a concentration of 0.05% is approved for children aged 2-5.
Barrier repair moisturizers
You can get these over the counter as well as by prescription. They help lock water into your skin, repair damage, and ease dryness, redness, and itching. Some products may have irritating fragrances or other ingredients, so ask your doctor or pharmacist which ones you should try or avoid.
Topical calcineurin inhibitors
When you have eczema, your immune system is more sensitive to allergens and irritants. Calcineurin inhibitors block your body’s production of calcineurin, a protein that is involved in activating immune cells. This helps reduce your immune system’s reaction and control inflammation.
Calcineurin inhibitors are an ointment available only with a prescription from your doctor. It’s important to protect your skin from the sun when using them as they can increase your skin’s sensitivity.
Immunosuppressants
Immunosuppressants help control your immune system and reduce its reaction to irritants. These are helpful if you have moderate to severe eczema and other treatments haven’t worked. They ease itching so you scratch less, and your skin has time to heal.
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