Could Your Fatigue Be From Fatty Liver Disease? Plus, 4 Other Early Symptoms

Progressive Symptoms

As fatty liver disease progresses, the buildup of fat causes inflammation in the liver. This stage of the disease may be called metabolic dysfunction-associated steatohepatitis (MASH) or alcohol-associated hepatitis, depending on the cause.56

Over time, inflammation can damage your liver and lead to fibrosis, which occurs when your body begins to make scar tissue in the liver. Inflammation damages liver cells, and scar tissue is your liver’s way of trying to repair those cells.7

Once fatty liver disease has progressed to MASH or alcohol-associated hepatitis, symptoms are more likely to occur.

Still, many people do not have noticeable symptoms at this point. Along with possible early-stage symptoms like fatigue, other signs and symptoms of progressing fatty liver disease may include:

  • Itchy skin
  • Increased thirst
  • Bloating
  • Decreased appetite
  • Loss of mental clarity
  • Mood swings
  • Edema (fluid buildup) in your lower legs
  • Fever (in those with alcohol-associated hepatitis)
  • Jaundice (yellowing of the eyes and skin)

Often, symptoms like these may indicate that fibrosis has progressed to cirrhosis (permanent scarring of the liver).7 In cirrhosis, scar tissue replaces healthy tissue and stops your liver from functioning properly.

End-Stage Symptoms

If fatty liver disease goes unmanaged, it may lead to cirrhosis.

Ultimately, cirrhosis can progress to end-stage liver disease, or liver failure. Liver failure means your liver can no longer perform its functions in the body. People with liver failure typically need a liver transplant to survive.9

Symptoms of cirrhosis and liver failure can include all the symptoms above, along with:

  • Nausea with vomiting
  • Weight loss
  • Muscle cramps or weakness
  • Muscle loss
  • Easy bleeding or bruising
  • Memory loss
  • Sleep disorders
  • Sexual dysfunction
  • Ascites (fluid buildup in the abdomen)

What Are the Symptoms in Children?

Although fatty liver disease most commonly affects older adults, it can also affect children.

As rates of obesity among children are rising, so are rates of fatty liver disease.8 Currently, up to 1 in 10 children ages 2-19 have MASLD.

Like adults, children with fatty liver disease may have no symptoms unless the condition has progressed to a more severe stage. Along with fatigue and abdominal discomfort, symptoms in children may include

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