Risk increased with higher cumulative doses and longer duration of use.
The link was strongest for medications with high anticholinergic activity—including some common muscle relaxants and bladder drugs.
Notably, short-term or occasional use (e.g., a few days of Benadryl for allergies) was not linked to increased risk.
⚠️ Why This Matters for Back Pain Sufferers
Back pain is one of the top reasons adults visit doctors—and muscle relaxants are among the most prescribed treatments, despite limited evidence they’re more effective than NSAIDs (like ibuprofen) or physical therapy.
Now, this study suggests that the convenience of a quick prescription may come with long-term cognitive costs, especially when used repeatedly or for months.
✅ What You Can Do
Don’t stop medication abruptly—especially if prescribed. Talk to your doctor first.
Ask: “Is this anticholinergic drug necessary long-term?”
Explore safer alternatives for back pain:
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