Common anticholinergic medications include:Muscle relaxants:
– Cyclobenzaprine (Flexeril)
– Orphenadrine (Norflex)
– Carisoprodol (Soma)
Antihistamines: Diphenhydramine (Benadryl)
Overactive bladder drugs: Oxybutynin (Ditropan)
Some antidepressants: Amitriptyline, paroxetine
Many of these—especially muscle relaxants like cyclobenzaprine—are frequently prescribed for acute back pain, often for weeks at a time.
📊 What the Study Found
Published in a leading neurology journal and tracking over 250,000 adults aged 55+, the study found that:
People who used strong anticholinergic drugs daily for 3+ years had a 50% higher risk of developing dementia compared to non-users.
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