Higher Doses = Higher Risk
Interestingly, the risk of cognitive decline seems to be cumulative, according to this previous study. The more pills you take in a lifetime, the higher your overall risk of developing dementia. Taking a few Benadryls here and there likely won’t affect dementia risk. However, taking them regularly over many years might.
Most Common Anticholinergic Drugs
There are many different types of anticholinergic medications prescribed under different names. Here’s a list of the most common types and their uses:
What does this all mean?
Given that research in this area is still relatively new, the results shouldn’t be viewed as conclusive but should be taken into consideration.
So, until further studies are done to confirm these findings, the logical advice is to try and minimize the use of anticholinergic drugs whenever possible. This goes double (or 2.5 times) for people with genetic predispositions for Alzheimer’s and quadruple for those with biomarkers for Alzheimer’s.
If you or a loved one are on one or many anticholinergic drugs, be sure to talk to your doctor about whether these drugs are the best options available and whether good non-anticholinergic alternatives are available.
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