Ozempic is essentially slowing down digestion. The psyllium husk is simply sitting in the stomach for longer.
An average of “15% of body weight can be lost with Wegovy,” William Yancy, MD, professor of medicine and director of the Lifestyle and Weight Management Center at Duke Health, told Health.
“With [psyllium husk] it might be a fraction of a percent, or maybe one or two percent if there’s any weight loss at all. So it’s not really a comparison,” said Dr. Yancy.
Psyllium husk is “not known as an effective weight loss strategy,” said Dr. Sonu. Other studies have shown that the fiber does not have any meaningful effect on weight.4
For Ozempic and psyllium husk’s other shared feature—namely, blood sugar control—again the two do not really compare, said Dr. Yancy.
“Ozempic acts like a hormone in the body,” said Dr. Yancy. It stimulates insulin release that helps control blood sugar.
Psyllium husk, on the other hand, traps some sugars in the digestive tract before they can be absorbed into the bloodstream.3
Who Should Take Psyllium Husk Supplements?
Psyllium husk is the latest in a long line of alleged “dupes” for semaglutide—TikTokers have dubbed the supplement berberine a natural Ozempic, while interest in laxatives, to appear thin or to address stomach issues, appears to be driving a nationwide shortage.
It’s easy to understand why. On the one hand, dieting and exercising to lose weight can seem daunting—a “magic pill” to expedite the process will likely always be popular.
Accessing the real weight loss medications can be difficult. Certain doses of Mounjaro, Wegovy, and Ozempic can be “in shortage.”56
Plus, drugs can be extremely expensive—without insurance, Ozempic can cost over $900 per month, though there are ways to lower the costs with coupons and insurance.
However, these supplements, laxatives, or other over-the-counter products will not work in the same way as prescription weight loss or type 2 diabetes medications.
“Ozempic or semaglutide or Wegovy—that’s a medicine that we’ve been waiting around [for] for decades,” said Dr. Yancy. “I don’t think there’s a way to replicate it in existing products, or over-the-counter products, or supplements.”
That being said, psyllium should not be written off completely, even though it may not be a good semaglutide replacement.
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